Premium
Genetic background of CTX‐M‐15‐producing Enterobacter hormaechei ST114 and Citrobacter freundii ST265 co‐infecting a free‐living green turtle ( Chelonia mydas )
Author(s) -
Goldberg Daphne W.,
Fernandes Miriam R.,
Sellera Fábio P.,
Costa Daniela G. C.,
Loureiro Bracarense Ana Paula,
Lincopan Nilton
Publication year - 2019
Publication title -
zoonoses and public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.87
H-Index - 65
eISSN - 1863-2378
pISSN - 1863-1959
DOI - 10.1111/zph.12572
Subject(s) - citrobacter freundii , biology , resistome , turtle (robot) , metagenomics , zoology , colonization , enterobacter , enterobacteriaceae , ecology , microbiology and biotechnology , mobile genetic elements , genome , genetics , gene , escherichia coli
CTX‐M‐type extended‐spectrum β‐lactamase (ESBL)‐producing Enterobacteriaceae have become identified in marine ecosystem constituting a serious ecological issue. In this respect, although contamination of coastal waters and seafood, and even colonization of seabirds and fishes have been increasingly reported, molecular data are lacking to elucidate the clinical impact of ESBL producers in infected marine animals. In this study, using a genomic approach, we have analysed the genetic background of CTX‐M‐15‐producing Enterobacter hormaechei (belonging to the international human clone ST114) and Citrobacter freundii (ST265) co‐infecting a free‐living green turtle ( Chelonia mydas ) suffering from septic arthritis, which progressed to generalized coelomitis and death. Wide resistome of these pathogens contributed to treatment failure and death of the animal.