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No Evidence of Dengue Virus Infections in Several Species of Bats Captured in Central and Southern Mexico
Author(s) -
CabreraRomo S.,
Max Ramirez C.,
RecioTótoro B.,
TolentinoChi J.,
Lanz H.,
Ángel R. M.,
SánchezCordero V.,
RodríguezMoreno Á.,
Ludert J. E.
Publication year - 2016
Publication title -
zoonoses and public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.87
H-Index - 65
eISSN - 1863-2378
pISSN - 1863-1959
DOI - 10.1111/zph.12276
Subject(s) - biology , dengue virus , virology , dengue fever , virus , plaque reduction neutralization test , antibody , neutralization , zoology , immunology
Summary Bats are reservoirs for viruses with zoonotic potential in the Americas, and scattered evidence exists suggesting that bats may act as reservoirs for dengue virus (DENV). To explore further the role of bats as part of DENV sylvatic cycles, 240 bats of 18 species were captured in 2 states of Mexico with contrasting ecological characteristics but concurrent DENV activity in humans. RT‐PCR analysis of RNA extracted from liver or spleen tissue from de bats failed to show evidence for the presence of DENV nucleic acids in these organs. In addition, plasma assayed by plaque reduction neutralization test showed no evidence of neutralizing anti‐DENV antibodies. These results suggest that American bats may not be reservoirs or amplification host for DENV infection.