Premium
Prevalence of Type VI Secretion System in Spanish Campylobacter jejuni Isolates
Author(s) -
UgarteRuiz M.,
Stabler R. A.,
Domínguez L.,
Porrero M. C.,
Wren B. W.,
Dorrell N.,
Gundogdu O.
Publication year - 2015
Publication title -
zoonoses and public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.87
H-Index - 65
eISSN - 1863-2378
pISSN - 1863-1959
DOI - 10.1111/zph.12176
Subject(s) - campylobacter jejuni , virulence , orfs , biology , microbiology and biotechnology , pathogenicity island , whole genome sequencing , genome , pathogenicity , gene , genetics , bacteria , open reading frame , peptide sequence
Summary Infections from Campylobacter jejuni pose a serious public health problem and are now considered the leading cause of foodborne bacterial gastroenteritis throughout the world. Sequencing of C. jejuni genomes has previously allowed a number of loci to be identified, which encode virulence factors that aid survival and pathogenicity. Recently, a Type VI secretion system (T6 SS ) consisting of 13 conserved genes was described in C. jejuni strains and recognised to promote pathogenicity and adaptation to the environment. In this study, we determined the presence of this T6 SS in 63 Spanish C. jejuni isolates from the food chain and urban effluents using whole‐genome sequencing. Our findings demonstrated that nine (14%) strains harboured the 13 ORF s found in prototype strain C. jejuni 108. Further studies will be necessary to determine the prevalence and importance of T6 SS ‐positive C. jejuni strains.