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Recurrent Temporary Paralysis Reported After Human Rabies Post‐Exposure Prophylaxis
Author(s) -
Dato V. M.,
Campagnolo E. R.,
Shah D. U.,
Bellush M. J.,
Rupprecht C. E.
Publication year - 2015
Publication title -
zoonoses and public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.87
H-Index - 65
eISSN - 1863-2378
pISSN - 1863-1959
DOI - 10.1111/zph.12143
Subject(s) - rabies , paralysis , medicine , post exposure prophylaxis , serology , adverse effect , pediatrics , anesthesia , virology , surgery , immunology , antibody
Summary Adverse events can occur after rabies post‐exposure prophylaxis ( PEP ), and linkage to causality is often difficult to determine. We report a case of recurrent temporary paralysis that began immediately after the initiation of rabies PEP in a man exposed to a bat. The recurrent temporary paralysis first occurred in the patient after his initial dose and then again after day 3 of his rabies PEP . The PEP was terminated prior to a serologic response. The patient continued to experience numerous discrete episodes of temporary paralysis for over two years.