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Early postoperative treatment of thyroidectomy scars using botulinum toxin: A split‐scar, double‐blind randomized controlled trial
Author(s) -
Kim Youn Sung,
Lee Hyun Joo,
Cho Sang Hyun,
Lee Jeong Deuk,
Kim Hei Sung
Publication year - 2014
Publication title -
wound repair and regeneration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.847
H-Index - 109
eISSN - 1524-475X
pISSN - 1067-1927
DOI - 10.1111/wrr.12204
Subject(s) - scars , medicine , saline , surgery , randomized controlled trial , double blind , thyroidectomy , botulinum toxin , anesthesia , placebo , thyroid , alternative medicine , pathology
Operational scars, especially those located on the exposed parts of the body, can be distressing. Despite high demand for an early intervention to minimize surgical scars, there is yet no universal consensus on optimal treatment. A split‐scar, double‐blind randomized controlled trial was held to assess the safety and efficacy of early postoperative botulinum toxin type A ( BTA ) injection in surgical scars. A single session of treatment was performed where BTA was allocated to one half of the scar and 0.9% saline to the control half. Scars were assessed using the modified Stony Brook Scar Evaluation Scale ( SBSES ) with standardized photographs. Fifteen patients completed the study, and their data were analyzed. At 6 months' follow‐up, a significant improvement in SBSES score was noted for the BTA ‐treated halves of the scars ( p < 0.001), with minimal change on the saline‐treated side ( p = 0.785). The mean calculated difference in SBSES scores (final/initial) between the BTA ‐treated side and the saline‐treated side was also significant ( p < 0.001). Early postoperative BTA injection was safe and effective in modulating thyroidectomy scars and may be a promising option for scar prevention.