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Effect of Metoclopramide on the Incidence of Early Postoperative Aspiration Pneumonia in Dogs with Acquired Idiopathic Laryngeal Paralysis
Author(s) -
Milovancev Milan,
Townsend Katy,
Spina Jason,
Hurley Connie,
Ralphs S. Christopher,
Trumpatori Brian,
Seguin Bernard,
Jermyn Kieri
Publication year - 2016
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/vsu.12491
Subject(s) - medicine , metoclopramide , aspiration pneumonia , anesthesia , laryngeal paralysis , surgery , perioperative , pneumonia , incidence (geometry) , paralysis , vomiting , physics , optics
Objective Evaluate the effect of a perioperative intravenous continuous rate infusion (CRI) of metoclopramide on the incidence of aspiration pneumonia in the short term postoperative period in dogs undergoing unilateral arytenoid lateralization. Study Design Prospective, randomized, multi‐center clinical trial. Animals 61 client‐owned dogs with idiopathic laryngeal paralysis and normal preoperative thoracic radiographs. Methods All dogs underwent unilateral arytenoid lateralization with a uniform anesthetic, analgesic, and management protocol. Dogs in the treatment group received an intravenous CRI of metoclopramide for 24 hours perioperative. All dogs were assessed for clinical signs of aspiration pneumonia based on the results of physical examination and owner interview up to the point of suture removal (10–14 days postoperative). Any dog with suspected aspiration pneumonia had thoracic radiographs performed. Results Six dogs developed aspiration pneumonia in the short term postoperative period (2/28 control dogs and 4/33 treated dogs), accounting for an overall frequency of 10% with no significant difference between control and treated dogs. No variables measured in the study were significantly different between control and treated dogs. Conclusions Perioperative metoclopramide, at the doses used in this study, did not affect the incidence of aspiration pneumonia in the short term postoperative period in dogs with idiopathic laryngeal paralysis undergoing unilateral arytenoid lateralization.