Premium
In the NAT era, is routine lookback to recipients still required when donors seroconvert for HIV infection?
Author(s) -
Vishram Bhavita,
Reynolds Claire,
Brailsford Susan R.,
Hewitt Patricia
Publication year - 2019
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/vox.12767
Subject(s) - nat , human immunodeficiency virus (hiv) , medicine , hiv screening , donation , virology , window period , immunology , men who have sex with men , antibody , serology , political science , syphilis , law , computer network , computer science
Human immuno virus screening assays have improved in sensitivity over the last 20 years and our data demonstrates that there is no evidence of missed HIV positive window period donations since the introduction of pooled HIV NAT screening. Here we recommend that extensive lookback investigations are not routinely required if the most recent negative donation is negative on individual sample HIV PCR testing.