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Metagenomics analysis of the virome of 300 concentrates from a Swiss platelet bank
Author(s) -
Brito Francisco,
Cordey Samuel,
Delwart Eric,
Deng Xutao,
Tirefort Diderik,
LemoineChaduc Coralie,
Zdobnov Evgeny,
Lecompte Thomas,
Kaiser Laurent,
WaldvogelAbramowski Sophie,
PreynatSeauve Olivier
Publication year - 2018
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/vox.12695
Subject(s) - human virome , metagenomics , platelet , biology , computational biology , immunology , gene , genetics
Background and objectives Platelet concentrates are frequently transfused to patients with reduced immunity. An exhaustive description of their viral content is needed to prevent unwanted infection. Material and methods To track viral sequences, a shotgun metagenomics approach was used on a bank of 300 platelets concentrates. Sequences were analysed through the diagnostics‐oriented pipeline ez VIR . Results We only observed viruses commonly described in healthy individuals. Conclusion Herein is reported the first viral landscape of a platelet concentrates bank.