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Correlation of the hypotonic shock response and extent of shape change with the new T hrombo LUX ™
Author(s) -
Kraemer L.,
Raczat T.,
Weiss D.R.,
Strobel J.,
Eckstein R.,
Ringwald J.
Publication year - 2015
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/vox.12268
Subject(s) - correlation , shock (circulatory) , chemistry , food science , medicine , mathematics , geometry
Thrombo LUX ( TLX )‐Score was compared with hypotonic shock response ( HSR ) and extent of shape change ( ESC ) in 99 samples from 42 platelet concentrates. Tests were performed in parallel and duplicate. Mean values for TLX Score, HSR and ESC were 30·3 ± 3·8%, 69·0 ± 12·2% and 23·2 ± 4·9%, respectively. We found no significant correlation between TLX Score and HSR or ESC ( r = −0·158, P = 0·118 and r = −115, P = 0·255, respectively), whereas HSR and ESC correlated significantly ( r = 0·351, P < 0·001). As TLX Score did not show significant correlation with HSR and ESC , the value of TLX for platelet quality testing remains unclear. Studies comparing these parameters with transfusion outcome are needed.