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Canine low‐grade intra‐orbital myxosarcoma: case report
Author(s) -
Campos Cecília B.,
Nunes Fernanda C.,
Gamba Conrado O.,
Damasceno Karine A.,
Souza Cristina M.,
Campos Liliane C.,
Cassali Geovanni D.
Publication year - 2015
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1111/vop.12183
Subject(s) - vimentin , trichrome stain , pathology , immunohistochemistry , stain , medicine , trichrome , masson's trichrome stain , anatomy , periodic acid–schiff stain , mitotic index , h&e stain , biology , staining , mitosis , microbiology and biotechnology
Objective The aim of this study was to evaluate important clinical, morphological, histopathological, histochemical, and immunohistochemical characteristics in order to establish the diagnosis and prognosis of a low‐grade intra‐orbital myxosarcoma. Animal studied A mongrel dog presented a 2‐year history of a neoplastic mass behind the right eye. Results The neoplasm presented a mesenchymal spindle and stellate cell proliferation with an abundant myxoid matrix, moderate anisocariosis, and a low mitotic index. It stained positive for vimentin, moderately positive for p eriodic acid‐ S chiff, and negative for G omori trichrome stain and α‐smooth muscle actin. Conclusions One year following surgical excision, the patient remains disease free. The histological findings established a diagnosis of a rare canine intra‐orbital low‐grade myxosarcoma.