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Intraocular sarcoma associated with a rupture lens in a rabbit ( Oryctolagus cuniculus )
Author(s) -
Dickinson Ryan,
Bauer Bianca,
Gardhouse Sara,
Grahn Bruce
Publication year - 2013
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1111/vop.12049
Subject(s) - rabbit (cipher) , lens (geology) , sarcoma , anatomy , biology , ophthalmology , pathology , medicine , computer science , paleontology , computer security
This case report describes the clinical manifestations and ocular pathology of an intraocular sarcoma in a spayed female 7‐year‐old rabbit that developed clinical signs consistent with phacoclastic uveitis at 6 months of age, which was left untreated for most of the next 6 years. Ophthalmologic examination confirmed pupillary occlusion, aqueous flare, fibrin, and lens debris within the anterior chamber of the right eye. The right eye was blind and phthisical. The tentative clinical diagnosis was chronic phacoclastic uveitis, and a routine transconjunctival enucleation of the right eye was completed. The globe was formalin‐fixed and submitted for histologic examination. Light microscopic examination revealed a ruptured cataractous lens, uveitis, retinal detachment, and an intraocular sarcoma centered around the lens. Immunohistochemical ( IHC ) staining was positive for smooth muscle actin and vimentin and negative for Desmin and cytokeratin intermediate filaments.