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Mean central corneal thickness and corneal power measurements in pigmented and white rabbits using Visante optical coherence tomography and ATLAS corneal topography
Author(s) -
Wang Xiaogang,
Dong Jing,
Wu Qiang
Publication year - 2014
Publication title -
veterinary ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.594
H-Index - 50
eISSN - 1463-5224
pISSN - 1463-5216
DOI - 10.1111/vop.12039
Subject(s) - meridian (astronomy) , ophthalmology , cornea , dioptre , optical coherence tomography , medicine , corneal topography , anatomy , visual acuity , physics , astronomy
Objective To document central corneal thickness (CCT) and power measurements in pigmented and white rabbits using Visante anterior segment optical coherence tomography ( AS ‐ OCT ) and the Humphrey ATLAS Corneal Topography System ( HACTS ). Animal studied Fourteen female rabbits (seven pigmented and seven white rabbits) were involved in this study. Procedure Twenty‐eight eyes underwent AS ‐ OCT and HACTS examination. Central corneal thickness, corneal power in the steepest and flattest meridians, astigmatism, pupil diameter ( PD ), and white‐to‐white ( WTW ) were calculated. Results The CCT was 390 ± 14.2 and 373 ± 7.2 μm for pigmented and white rabbits, respectively. The CCT values showed statistical difference between the two breeds ( P = 0.017). The corneal power in the steepest meridian was 44.6 ± 1.9 Diopter (D) in pigmented rabbits and 47.8 ± 1.5 D in white rabbits. The corneal power in the flattest meridian was 44.0 ± 2.1 D in pigmented rabbits and 47.4 ± 1.5 D in white rabbits. The astigmatism, PD , and WTW values were 0.6 ± 0.22 D, 7.9 ± 0.9, and 14.5 ± 0.1 mm in pigmented rabbits, respectively. The corresponding values in white rabbits were 0.4 ± 0.23 D, 7.5 ± 0.5, and 13.5 ± 0.2 mm. There was a statistically significant difference in corneal power in the steepest and flattest meridians and for WTW . No such difference was observed for astigmatism or PD between them. Conclusions Differences exist in the CCT , corneal power, and WTW between 5‐month‐old pigmented and white rabbits. Such difference should be considered when designing cornea‐related experiments in rabbits.