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Therapeutic plasma exchange to mitigate flunixin meglumine overdose in a cria
Author(s) -
Dixon Claire E.,
Kelley Denise,
Froehlich Jacob Michael,
Gruntman Alisha,
Oura Trisha,
Mazan Melissa R.,
Labato Mary Anna
Publication year - 2021
Publication title -
journal of veterinary emergency and critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 47
eISSN - 1476-4431
pISSN - 1479-3261
DOI - 10.1111/vec.13071
Subject(s) - medicine , urinary system , hydronephrosis , meglumine , anesthesia , magnetic resonance imaging , radiology
Objective To describe the use of therapeutic plasma exchange (TPE) in the treatment of flunixin meglumine overdose in a cria. Case Summary A 3‐day‐old alpaca cria was diagnosed with ureteral obstruction and agenesis resulting in severe bilateral hydronephrosis. During hospitalization, the cria inadvertently received a flunixin meglumine overdose of >65 mg/kg. Here, we report the use of lipid emulsion and TPE to mitigate flunixin meglumine toxicosis. TPE appeared to prevent any flunixin‐induced kidney or gastrointestinal injury, even in a patient with congenital defects of the urinary tract. New Information Provided This is the first report of the use of TPE in a cria.