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Association of Veterinary Hematology and Transfusion Medicine (AVHTM) transfusion reaction small animal consensus statement (TRACS). Part 3: Diagnosis and treatment
Author(s) -
Odunayo Adesola,
Nash Katherine J,
Davidow Elizabeth B.,
Blois Shauna L.,
GoyThollot Isabelle,
Harris Lauren,
Humm Karen,
Musulin Sarah,
Sharp Claire R.,
Spada Eva,
Thomason John,
Walton Jenny,
Jane Wardrop K.
Publication year - 2021
Publication title -
journal of veterinary emergency and critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 47
eISSN - 1476-4431
pISSN - 1479-3261
DOI - 10.1111/vec.13043
Subject(s) - medicine , medline , transfusion medicine , delphi method , population , evidence based medicine , specialty , intensive care medicine , family medicine , blood transfusion , alternative medicine , pathology , statistics , mathematics , environmental health , political science , law
Objective To systematically review available evidence to develop guidelines for diagnosis and treatment of transfusion‐associated reactions in dogs and cats. Design Standardized and systemic evaluation of the literature (identified through Medline via PubMed and Google Scholar searches) was carried out for identified transfusion reaction types in dogs and cats. The available evidence was evaluated using PICO (Population, Intervention, Comparison, Outcome) questions generated for each reaction type. The evidence was categorized by level of evidence (LOE) and quality (Good, Fair, or Poor). Guidelines, diagnostic, and treatment algorithms were generated based on the evaluation of the evidence. Consensus on the final guidelines was achieved through Delphi‐style surveys. Draft recommendations were disseminated through veterinary specialty listservs for review and comments, which were evaluated and integrated prior to final publication. Results Medline via PubMed and Google Scholar databases were searched. There were 14 Population Intervention Comparison Outcome questions identified and corresponding worksheets were developed focusing on the diagnosis and treatment of transfusion‐associated reactions in dogs and cats. Fourteen guidelines and four algorithms were developed with a high degree of consensus. Conclusions This systematic evidence evaluation process yielded recommended diagnostic and treatment algorithms for use in practice. However, significant knowledge gaps were identified, demonstrating the need for additional research in veterinary transfusion medicine.