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Prevalence and impact of cholecystitis on outcome in dogs with gallbladder mucocele
Author(s) -
Rogers Erin,
Jaffey Jared A.,
Graham Amber,
Hostnik Eric T.,
Jacobs Casandra,
FoxAlvarez William,
Van Eerde Eric,
Arango John,
Williams Fred,
DeClue Amy E.
Publication year - 2019
Publication title -
journal of veterinary emergency and critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 47
eISSN - 1476-4431
pISSN - 1479-3261
DOI - 10.1111/vec.12910
Subject(s) - medicine , cholecystitis , gallbladder , mucocele , gastroenterology , gallbladder disease , surgery
Background Gallbladder mucocele is a potentially life‐threatening extrahepatic biliary disease in dogs. The primary aims of this study were to evaluate the prevalence of cholecystitis in dogs with gross and histopathologically confirmed gallbladder mucocele and to investigate if there is an association between cholecystitis, including its subtypes (eg, acute, acute on chronic, with necrosis, chronic), and survival. Our secondary objective was to evaluate if there is an association between cholecystitis and intraoperative bacteriological culture positivity. Key Findings Two hundred nineteen dogs with gallbladder mucocele were included in this multi‐institutional retrospective study, of which 63 (28.8%) dogs had histopathological evidence of cholecystitis. The most common forms of cholecystitis were acute on chronic (n = 22/63, 34.9%) and with necrosis (n = 20, 31.7%). Thirty‐one (14.1%) dogs had growth of at least 1 bacterial isolate; however, 88.7% had antimicrobials administered within the 48 hours before surgery or intraoperatively. There was not an association between cholecystitis or its subtypes and survival. Furthermore, there was not an association between cholecystitis and intraoperative bacteriological culture positivity. A total of 38 (17.4%) dogs either died or were euthanized during hospitalization. Significance Cholecystitis is a common comorbidity in dogs with gallbladder mucocele but was not associated with decreased survival.

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