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Determination of reference intervals of acid‐base parameters in clinically healthy dogs
Author(s) -
VanovaUhrikova Ivana,
RauserovaLexmaulova Leona,
Rehakova Kristina,
Scheer Peter,
Doubek Jaroslav
Publication year - 2017
Publication title -
journal of veterinary emergency and critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 47
eISSN - 1476-4431
pISSN - 1479-3261
DOI - 10.1111/vec.12589
Subject(s) - anion gap , medicine , base excess , arterial blood , pco2 , bicarbonate , sodium , venous blood , albumin , potassium , population , anesthesia , confidence interval , acidosis , chloride , jugular vein , acid–base homeostasis , chemistry , environmental health , organic chemistry
Objective To establish reference intervals for traditionally‐ and Stewart's approach‐determined acid‐base parameters in a population of clinically healthy dogs. Design Prospective study (June 2011–September 2012). Setting Veterinary teaching hospital. Animals Two hundred twenty‐four client‐owned, clinically healthy dogs. Interventions Blood was collected from the jugular vein and the dorsal pedal artery. Measurements and Main Results In the whole blood samples, pH, PCO 2 , and PO 2 were measured and HCO 3 − , standard and total bicarbonate, base excess, oxygen content, and alveolar–arterial oxygen differences were calculated. Plasma sodium, potassium, chloride, calcium, albumin, and lactate concentrations were measured and the following parameters were calculated separately for venous and arterial samples: anion gap, anion gap corrected for albumin and phosphate, sodium chloride difference and ratio, chloride gap, strong ion difference, strong ion gap, and unmeasured anions. Conclusion Reference intervals for traditionally‐ and Stewart's approach‐determined acid‐base parameters were established for venous and arterial blood in dogs.