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Assessment of coagulation utilizing thromboelastometry in dogs undergoing orthopedic surgery
Author(s) -
Bruno Barbara,
Maurella Cristiana,
Falco Sara,
Tarducci Alberto,
Zanatta Renato,
Gianella Paola,
D'Angelo Antonio,
Piras Lisa,
Di Bella Andrea,
Borrelli Antonio
Publication year - 2015
Publication title -
journal of veterinary emergency and critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 47
eISSN - 1476-4431
pISSN - 1479-3261
DOI - 10.1111/vec.12300
Subject(s) - medicine , thromboelastometry , orthopedic surgery , thrombelastography , surgery , coagulation , anesthesia , coagulopathy
Objective To evaluate blood coagulation using thromboelastometry in dogs following orthopedic surgery. Design Longitudinal observational study. Setting University veterinary teaching hospital. Animals Thirty‐four adult client‐owned dogs. Measurements and Main Results Dogs undergoing elective or emergency orthopedic surgery had whole blood collected before (T0), at 24 hours (T1), and 1 week (T2) after surgery. Whole blood from each dog was collected by jugular venipuncture using a 20‐Ga needle and minimum venous stasis. The blood was placed into tubes containing 3.8% trisodium citrate (1 part citrate: 9 parts blood) and rested at 37°C. Coagulation was evaluated by means of thromboelastometry using the in‐TEM, ex‐TEM, and fib‐TEM assays. Statistically significant increases ( P < 0.05) in maximum clot firmness (MCF) from T0 to T1 in the in‐TEM and fib‐TEM profiles (both P = 0.0001), from T0 to T2 in the in‐TEM, ex‐TEM, and fib‐TEM profiles ( P = 0.012, P = 0.037, and P = 0.0001, respectively), and from T1 to T2 in the fib‐TEM profile ( P = 0.039) were noted. The α angle increased from T0 to T2 in the in‐TEM and ex‐TEM profiles ( P = 0.019 and P = 0.036, respectively). All results were, however, within the institutional reference ranges. Conclusions In this study, unlike the hypercoagulability observed in human orthopedic patients, a hypercoagulable state as measured by thromboelastometry did not develop in dogs following orthopedic surgery.