Premium
Preliminary evaluation of the utility of comparing SpO 2 /FiO 2 and PaO 2 /FiO 2 ratios in dogs
Author(s) -
Calabro Janine M.,
Prittie Jennifer E.,
Palma Douglas A.
Publication year - 2013
Publication title -
journal of veterinary emergency and critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 47
eISSN - 1476-4431
pISSN - 1479-3261
DOI - 10.1111/vec.12050
Subject(s) - medicine , pulse oximetry , anesthesia , hypoxemia , oxygenation , arterial blood , fraction of inspired oxygen , population , oxygen saturation , venous blood , mechanical ventilation , oxygen , chemistry , environmental health , organic chemistry
Objective To determine whether the ratio of pulse oximetry saturation/fraction of inspired oxygen (SpO 2 /FiO 2 , [SF]) correlates with the ratio of partial pressure of oxygen in arterial blood/FiO 2 (PaO 2 /FiO 2 , [PF]) in dogs. Design Prospective, observational pilot study. Setting Urban tertiary veterinary referral center. Animals Thirty‐eight client‐owned dogs requiring assessment of oxygenation. Interventions None. Measurements and Main Results Arterial blood gas analysis with co‐oximetry was performed on samples obtained from the dorsal pedal artery. Median SpO 2 was 91.5% (range 80–97%) and median PaO 2 was 70.1 mmHg (range 44.5–103.8 mmHg). Hypoventilation was uncommon and venous admixture was the predominant cause of hypoxemia in this population. Median SF was 435.7 (range 381.0–461.9) and median PF was 334.0 (range 211.9–494.3). Nine dogs (23.6%) had PF <300; no dogs had PF below 200. SF and PF were correlated (ρ = 0.618, P < 0.01). Conclusions SF and PF in dogs spontaneously breathing room air have good correlation, suggesting that SF may be a useful, noninvasive surrogate for PF when assessing oxygenation in canine patients. Further studies are warranted to confirm and validate this relationship in spontaneously breathing and mechanically ventilated dogs on varying levels of FiO 2 and to assess the ability of SF to predict outcome.