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Efficacy of fluralaner in 17 dogs with sarcoptic mange
Author(s) -
Romero Camilo,
Heredia Rafael,
Pineda Jocelyn,
Serrano Jonathan A.,
Mendoza Germán D.,
Trápala Porfirio,
Cordero Alberto M.
Publication year - 2016
Publication title -
veterinary dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.744
H-Index - 60
eISSN - 1365-3164
pISSN - 0959-4493
DOI - 10.1111/vde.12363
Subject(s) - mange , sarcoptes scabiei , medicine , scabies , lesion , veterinary medicine , dermatology , surgery
Background There are few licensed options for the treatment of canine sarcoptic mange. Objective To evaluate the efficacy of fluralaner in dogs with sarcoptic mange infestation. Animals Seventeen dogs with a diagnosis of Sarcoptes scabiei based on positive skin scrapings. Methods A single dose of oral fluralaner was administered according to the manufacturer's instructions. Assessments of pruritus and lesions were performed every 7 days for 1 month. Results By Day 14 post‐treatment, skin scrapings from all dogs were negative for mites. At the beginning of the study there was a negative correlation between body weight of the subject and pruritus [Pearson correlation coefficient (PCC) = −0.396, P = 0.007] and a positive correlation between pruritus and lesion severity (PCC 0.755, P = 0.0001). Significant decreases in lesion size and pruritus were observed within the first 14–21 days, respectively, and improvement in these parameters continued until the end of the study at Day 28. Conclusion Fluralaner was effective in eliminating scabies mites within 14 days and significantly resolved the clinical signs associated with sarcoptic mange within 21 days after a single dose.