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Marginal zone lymphoma in a dog
Author(s) -
Burgess Hilary J.,
MacDonald Dickinson Valerie,
Kerr Moira,
Bienzle Dorothee
Publication year - 2020
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/vcp.12874
Subject(s) - lymphoma , histopathology , marginal zone , medicine , lymph node , canine lymphoma , pathology , generalized lymphadenopathy , population , chemotherapy , cytology , presentation (obstetrics) , radiology , immunology , b cell , antibody , environmental health
A 13‐year‐old spayed female American Cocker Spaniel was presented for evaluation of a cough and weight loss. Physical exam revealed generalized lymphadenopathy. The patient was diagnosed with marginal zone lymphoma (MZL) on histopathology of an extirpated lymph node. This report demonstrates an unusual case of a pleomorphic neoplastic population documented on cytologic evaluation that had moncytoid features and peripheral blood involvement; a previously undocumented IgG1 monoclonal gammopathy was also an interesting feature of this canine MZL. The patient did not undergo chemotherapy for lymphoma and was euthanized over 4 years after the initial presentation.