Premium
Reference intervals for coagulation variables in healthy adult domestic goats ( Capra aegagrus hircus )
Author(s) -
Zersen Kristin M.,
Russell Moore A,
Olver Christine S.,
Mathis Justin C.
Publication year - 2018
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/vcp.12621
Subject(s) - fibrinogen , antithrombin , coagulation , prothrombin time , medicine , gastroenterology , immunology , heparin
Background Coagulation has not been studied extensively in adult goats, and reference intervals (RIs) for coagulation variables have not yet been established and would be clinically useful. Objectives The goal of this study was to establish coagulation variable RI s in adult goats for future coagulation interpretation. Methods Blood samples from 40 healthy adult goats were collected, and assays for PT , APTT , D‐dimers, antithrombin III , and fibrinogen were performed. Coagulation variable RI s were established using the Reference Value Advisor v2.1. Results The RI s included: PT , 15.7‐19.8 seconds; APTT , 16.2‐24.3 seconds; D‐dimer, 0‐0.68 μg/mL; antithrombin III , 108.6%‐156.5%; fibrinogen, 89.5‐303.2 mg/dL. Conclusions In this brief communication, we report the RI s for coagulation variables in healthy adult goats. Further research will be needed to identify coagulation changes that are associated with specific disease processes of goats.