Premium
Mast cell and plasma cell collision tumor in the spleen of a dog
Author(s) -
Pallatto Valarie A.,
Bechtold Molly A.
Publication year - 2018
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/vcp.12596
Subject(s) - spleen , immunofixation , pathology , plasma cell , serum protein electrophoresis , antibody , medicine , mast cell , urine , cytology , ultrasound , plasma cell neoplasm , vomiting , monoclonal , immunology , plasmacytoma , bone marrow , multiple myeloma , monoclonal antibody , radiology
Abstract A 9‐year‐old spayed female English Mastiff was referred for outpatient ultrasound due to a 3‐week history of weight loss, vomiting, and decreased appetite. Abdominal ultrasound showed multiple splenic masses of varying sizes and serum chemistry panel showed hyperglobulinemia. Cytologic examination of fine‐needle aspirates of the splenic masses indicated a mast cell and plasma cell collision tumor. Results of serum and urine protein electrophoresis and immunofixation indicated the plasma cell neoplasia was producing IgA immunoglobulins.