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Analysis of synovial fluid of the Capybara's stifle joints
Author(s) -
Brombini Giovanna C.,
Rahal Sheila C.,
Bergamini Bruno C. S.,
Lopes Raimundo S.,
Santos Ivan F. C.,
Schimming Bruno C.
Publication year - 2017
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/vcp.12449
Subject(s) - synovial fluid , stifle joint , cytology , pathology , peripheral blood mononuclear cell , cats , mucin , medicine , chemistry , osteoarthritis , biology , anatomy , in vitro , cruciate ligament , biochemistry , anterior cruciate ligament , alternative medicine
Background Although normal synovial fluid has been well characterized in domestic animals such as dogs, cats, horses, and cows, the available information on larger rodents is scarce. Objectives The purpose of the study was to analyze the physical, chemical, and cytologic characteristics of the synovial fluid in stifle joints of Capybaras. Methods Five free‐ranging adult female Capybaras ( Hydrochoerus hydrochaeris ), weighing from 37 to 56 kg were used. Synovial fluid was obtained by aspiration of 10 stifle joints. Samples were analyzed for physical, chemical, and cytologic properties. Results Spontaneous clotting was negative in 9 samples. Most synovial fluids had pH 8, and protein concentrations ranged from 1.6 to 3.6 g/dL. The mucin clot test was good in all 6 samples that were tested. Nucleated cell counts ranged from 140 to 508 cells/μL. Relative differential leukocyte counts demonstrated a predominance of mononuclear cells (97.6%), including 76.2% undifferentiated mononuclear cells, 18.1% macrophages, and 3.66% lymphocytes. Polymorphonuclear cells included 1.83% neutrophils and 0.2% eosinophils. Conclusion The synovial stifle joint fluid of healthy free‐ranging adult Capybaras is clear, colorless, viscous, and with chemical features and cytologic findings similar to those seen in domestic animals.