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Nodular granulomatous glossitis as the sole clinical sign in canine leishmaniosis
Author(s) -
Tangalidi Melpomeni K.,
Oikonomidis Ioannis L.,
Psalla Dimitra,
Papadimitriou Serafim,
KritsepiKonstantinou Maria,
Mylonakis Mathios E.
Publication year - 2016
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/vcp.12416
Subject(s) - histopathology , pathology , medicine , glossitis , tongue , leishmania infantum , miltefosine , dermatology , leishmaniasis , visceral leishmaniasis
A 5.5‐year‐old, intact male Rottweiler dog was admitted with a history of multifocal nodular tongue lesions which progressively deteriorated during the previous year. Physical examination revealed several reddish nodules with central depression on the surface of the tongue in an otherwise healthy dog. Clinicopathologic abnormalities included eosinophilia and hyperproteinemia. Lingual nodule cytopathology, histopathology, and immunohistochemistry revealed Leishmania spp. amastigotes and a severe granulomatous glossitis. The dog was also seroreactive to L infantum antigens by an indirect immunofluorescence assay. Clinical reevaluation 3 months after the institution of treatment with allopurinol and miltefosine indicated that the nodular lesions had completely regressed. In endemic areas, lingual nodular lesions may rarely be the sole clinical sign of canine leishmaniosis. Standard medical treatment may provide an excellent prognosis.