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Antibiotic prophylaxis in veterinary cancer chemotherapy: A review and recommendations
Author(s) -
Bisson J. L.,
Argyle D. J.,
Argyle S. A.
Publication year - 2018
Publication title -
veterinary and comparative oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 34
eISSN - 1476-5829
pISSN - 1476-5810
DOI - 10.1111/vco.12406
Subject(s) - medicine , antimicrobial chemotherapy , antimicrobial , intensive care medicine , antimicrobial stewardship , antibiotics , antibiotic resistance , cancer chemotherapy , neutropenia , chemotherapy , cancer , adverse effect , incidence (geometry) , drug resistance , veterinary medicine , microbiology and biotechnology , biology , physics , optics
Bacterial infection following cancer chemotherapy‐induced neutropenia is a serious cause of morbidity and mortality in human and veterinary patients. Antimicrobial prophylaxis is controversial in the human oncology field, as any decreased incidence in bacterial infections is countered by patient adverse effects and increased antimicrobial resistance. Comprehensive guidelines exist to aid human oncologists in prescribing antimicrobial prophylaxis but similar recommendations are not available in veterinary literature. As the veterinarian's role in antimicrobial stewardship is increasingly emphasized, it is vital that veterinary oncologists implement appropriate antimicrobial use. By considering the available human and veterinary literature we present an overview of current clinical practices and are able to suggest recommendations for prophylactic antimicrobial use in veterinary cancer chemotherapy patients.