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Complications of polytetrafluoroethylene graft use in middle hepatic vein reconstruction in living donor liver transplantation: a retrospective, single‐centre, long‐term, real‐world experience
Author(s) -
Woo Hye Young,
Hong Suk Kyun,
Cho JaeHyung,
Lee JeongMoo,
Choi YoungRok,
Yi NamJoon,
Lee KwangWoong,
Suh KyungSuk
Publication year - 2021
Publication title -
transplant international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 82
eISSN - 1432-2277
pISSN - 0934-0874
DOI - 10.1111/tri.13807
Subject(s) - medicine , surgery , duodenum , liver transplantation , retrospective cohort study , anastomosis , complication , vein , bile duct , transplantation
Summary In living donor liver transplantation (LDLT) of the right lobe, polytetrafluoroethylene (PTFE) grafts may be used for anterior drainage. This study aimed to determine the risk factors of PTFE graft‐associated complications. Data from patients who underwent LDLT of the right lobe with middle hepatic vein reconstruction using PTFE grafts between January 2005 and December 2012 were retrospectively reviewed. Among 360 patients, PTFE graft‐associated complications occurred in 17 patients (group B) (4.7%); recipients without these complications comprised group A (95.3%). The 1‐, 6‐ and 12‐month patency rates were significantly lower in group B ( P  < 0.001, P  = 0.002 and P  = 0.007). In group B, eight patients (47.1%) required surgical intervention, three patients (17.6%) suffered from infectious complications, and 14 patients (82.4%) experienced PTFE graft migration into the adjacent organs, namely the common bile duct ( n  = 3, 17.6%), stomach ( n  = 1, 5.9%), duodenum ( n  = 5, 29.4%) and jejunum ( n  = 5, 29.4%). The proportion of recipients who underwent hepaticojejunostomy, had abdominal adhesions and received interventions in/around the liver after LDLT was higher in group B ( P  < 0.001). Although the incidence of PTFE graft‐associated complication is low, close long‐term follow‐up is needed, especially in patients with risk factors.

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