Open AccessLaparoscopic sleeve gastrectomy for morbid obesity in renal transplantation candidates: a matched case–control study
Author(s) -
Gaillard Martin,
Tranchart Hadrien,
Beaudreuil Séverine,
Lebrun Amandine,
Voican Cosmin Sebastian,
Lainas Panagiotis,
Courie Rodi,
Perlemuter Gabriel,
Parier Bastien,
Hammoudi Yacine,
Durrbach Antoine,
Dagher Ibrahim
Publication year - 2020
Publication title -
transplant international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 82
eISSN - 1432-2277
pISSN - 0934-0874
DOI - 10.1111/tri.13637
Subject(s) - medicine , contraindication , transplantation , surgery , end stage renal disease , sleeve gastrectomy , obesity , weight loss , hemodialysis , gastric bypass , alternative medicine , pathology
Obesity has become an important issue in patients with end‐stage renal disease (ESRD). Since it is considered a relative contraindication for renal transplantation, bariatric surgery has been advocated to treat morbid obesity in transplant candidates, and laparoscopic sleeve gastrectomy (LSG) is the most reported procedure. However, comparative data regarding outcomes of LSG in patients with or without ESRD are scarce. Consecutive patients with ESRD ( n = 29) undergoing LSG were compared with matched patients with normal renal function undergoing LSG in a 1:3 ratio using propensity score adjustment. Data were collected from a prospective database. Eligibility for transplantation was also studied. A lower weight loss (20 kg (16–30)) was observed in patients with ESRD within the first year as compared to matched patients (28 kg (21–34)) ( P < 0.05). After a median follow‐up of 30 (19–50) months in the ESRD group, contraindication due to morbid obesity was lifted in 20 patients. Twelve patients underwent transplantation. In patients with ESRD potentially eligible for transplantation, LSG allows similar weight loss in comparison with matched patients with normal renal function, enabling lifting contraindication for transplantation due to morbid obesity in the majority of patients within the first postoperative year.