Open AccessA randomized, controlled, behavioral intervention to promote walking after abdominal organ transplantation: results from the LIFT study
Author(s) -
Serper Marina,
Barankay Iwan,
Chadha Sakshum,
Shults Justine,
Jones Lauren S.,
Olthoff Kim M.,
Reese Peter P.
Publication year - 2020
Publication title -
transplant international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 82
eISSN - 1432-2277
pISSN - 0934-0874
DOI - 10.1111/tri.13570
Subject(s) - medicine , randomized controlled trial , intervention (counseling) , organ transplantation , physical therapy , lift (data mining) , transplantation , physical medicine and rehabilitation , intensive care medicine , psychiatry , data mining , computer science
Summary Kidney transplant recipients (KTRs) and liver transplant recipients (LTRs) have significant post‐transplant weight gain and low physical activity. We conducted a home‐based, remotely monitored intervention using wearable accelerometer devices to promote post‐transplant physical activity. We randomized 61 KTRs and 66 LTRs within 24 months of transplant to: (i) control, (ii) accelerometer or (iii) intervention: accelerometer paired with financial incentives and health engagement questions to increase steps by 15% from baseline every 2 weeks. The primary outcome was weight change. A co‐primary outcome for the two accelerometer arms was steps. Participants were recruited at a median of 9.5 [3–17] months post‐transplant. At 3 months, there were no significant differences in weight change across the three arms. The intervention arm was more likely to achieve ≥7000 steps compared to control with device (OR 1.99, 95% CI: 1.03–3.87); effect remained significant after adjusting for demographics, allograft, time from transplant and baseline weight. Adherence to target step goals was 74% in the intervention arm, 84% of health engagement questions were answered correctly. A pilot study with financial incentives and health engagement questions was feasible and led KTRs and LTRs to walk more, but did not affect weight. A definitive trial is warranted.