Open AccessThe quality of life in type I diabetic patients with end‐stage kidney disease before and after simultaneous pancreas‐kidney transplantation: a single‐center prospective study
Author(s) -
Posegger Karin Romano,
Linhares Marcelo Moura,
Mucci Samantha,
Romano Thais Malta,
Gonzalez Adriano M.,
Salzedas Netto Alcides A.,
Rangel Érika Bevilaqua,
Lopes Filho Gaspar de Jesus,
SilvaJunior Helio Tedesco,
MedinaPestana Jose
Publication year - 2020
Publication title -
transplant international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 82
eISSN - 1432-2277
pISSN - 0934-0874
DOI - 10.1111/tri.13562
Subject(s) - medicine , single center , pancreas transplantation , end stage renal disease , kidney transplantation , transplantation , pancreas , kidney , nephrology , prospective cohort study , stage (stratigraphy) , quality of life (healthcare) , urology , surgery , disease , nursing , paleontology , biology
Summary Simultaneous pancreas‐kidney transplantation ( SPKT ) aimed at increasing the life expectancy for diabetic patients with end‐stage kidney disease ( ESKD ). However, the risks of surgery complications and immunosuppression therapy make it unclear if the SPKT positively impacts patient's quality of life (QoL). Using the Kidney Disease Quality of Life—Short‐Form Health Survey ( KDQOL ‐ SF 36) and Problems Areas in Diabetes ( PAID ) measurement tools, we compared the QoL of 57 patients on the pretransplant waiting list with that of 103 patients who had undergone SPKT . Posttransplantation patients were assessed within different time intervals (<1, 1–3, and >3 years). Mean KDQOL ‐ SF 36 scores were better among posttransplantation patients in the SF 36 and KDQOL domains. It was also observed patients’ stress reduction in PAID mean score ( P = 0.011) after SPKT . We concluded that patients receiving SPKT had a better perception of QoL than did patients on the waiting list, and this positive perception remained almost entirely comparable over the three different intervals of the posttransplantation time. These positive results showed better outcomes when excluding patients that lost pancreas graft function. Further research is needed to compare diabetic patients with kidney transplant alone using specific measurement tools to evaluate patient's QoL.