Open AccessEx‐vivo lung perfusion
Author(s) -
Raemdonck Dirk,
Neyrinck Arne,
Cypel Marcelo,
Keshavjee Shaf
Publication year - 2015
Publication title -
transplant international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 82
eISSN - 1432-2277
pISSN - 0934-0874
DOI - 10.1111/tri.12317
Subject(s) - medicine , ex vivo , lung transplantation , perfusion , lung , clinical trial , transplantation , in vivo , intensive care medicine , pathology , microbiology and biotechnology , biology
Summary This review outlines the new and promising technique of ex vivo lung perfusion and its clinical potential to increase the number of transplantable lungs and to improve the early and late outcome after transplantation. The rationale, the experimental background, the technique and protocols, and available devices for ex vivo lung perfusion are discussed. The current clinical experience worldwide and ongoing clinical trials are reviewed.