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Transfusion management for children supported by extracorporeal membrane oxygenation
Author(s) -
Karam Oliver,
Nellis Marianne E.
Publication year - 2021
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/trf.16272
Subject(s) - extracorporeal membrane oxygenation , medicine , coagulopathy , intensive care medicine , expert opinion , blood transfusion , anesthesia , surgery
Key Ideas Due to the patients' underlying illness, in combination with circuit‐induced coagulopathy, as well as PLT dysfunction, children supported by ECMO are a risk of receiving large volumes of blood components. Given the increasing use of modified blood products and newer biologics, it is unknown whether these products have equal efficacy and safety, in ECMO. The majority of guidance for transfusion therapy is based on expert opinion alone, and research on indications for RBC, plasma, and PLT transfusions for children on ECMO should be a priority.