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CORS ( CROM20 ): A new high‐prevalence antigen in the Cromer blood group system
Author(s) -
Vrignaud Cédric,
Chiaroni Jacques,
DurieuxRoussel Elisabeth,
Le Van Kim Caroline,
Azouzi Slim,
Peyrard Thierry
Publication year - 2020
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/trf.16052
Subject(s) - antigen , proband , blood group antigens , glycine , biology , gene , microbiology and biotechnology , chemistry , immunology , genetics , amino acid , mutation
The Cromer blood group system consists of 19 antigens (16 of high prevalence and 3 of low prevalence). This study describes the identification and characterization of a new Cromer high‐prevalence antigen, named CORS. The CORS‐negative proband carries a c.713G>A substitution in the CD55 gene, resulting in the substitution of glycine 238 into a glutamic acid (p.Gly238Glu).