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Zika virus and its implications on cord blood banking and transplantation
Author(s) -
Stone Elizabeth F.,
Shaz Beth H.
Publication year - 2020
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/trf.15771
Subject(s) - umbilical cord , zika virus , medicine , transplantation , cord blood , hematopoietic stem cell transplantation , transmission (telecommunications) , umbilical cord blood transplantation , immunology , virus , intensive care medicine , electrical engineering , engineering
KEY IDEAS Umbilical cord blood is an important cellular therapy product used for hematopoietic stem cell transplantation, but the US Food and Drug Administration guidance regarding donor screening to reduce the risk of Zika transmission has decreased the number of licensed, eligible cord blood units available for transplantation. There is a crucial need for updated travel risk assessment for Zika virus transmission, validated screening tests for Zika virus in umbilical cord blood, and further research on Zika virus transmissibility due to umbilical cord blood products to ensure that umbilical cord blood and related tissues are safe and available for transplantation.