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Bloodless medicine: current strategies and emerging treatment paradigms
Author(s) -
Resar Linda M.S.,
Wick Elizabeth C.,
Almasri Talal Nael,
Dackiw Elizabeth A.,
Ness Paul M.,
Frank Steven M.
Publication year - 2016
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/trf.13736
Subject(s) - medicine , phlebotomy , intensive care medicine , anemia , blood loss , retrospective cohort study , medline , surgery , political science , law
BACKGROUND Advances in our understanding of the risks associated with allogeneic blood transfusions (ABTs) and the growing number of patients who wish to avoid ABTs have led to the emergence of new treatment paradigms for “bloodless” medicine and surgery. STUDY DESIGN AND METHODS Here, we review prior studies and summarize current strategies for bloodless care used at our institution. We advocate three basic principles: 1) diagnosing and aggressively treating anemia, 2) minimizing blood loss from laboratory testing and invasive procedures, and 3) identifying and managing bleeding diatheses. Anemia is treated with erythropoiesis‐stimulating agents as well as iron, folate, and B12 when indicated. Low‐volume phlebotomy tubes are used for laboratory testing. Autologous blood salvage is used for childbirth and surgical patients who have the potential for substantial bleeding. RESULTS Although there have been few retrospective studies and no prospective studies to guide management, prior studies suggest that outcomes for surgical patients managed without ABTs are comparable to those of historic controls. CONCLUSIONS Given the emerging evidence that patients who avoid ABTs do as well if not better than patients who accept ABTs, further efforts are needed to determine whether all patients could benefit from bloodless strategies. Bloodless approaches in selected patients could reduce risks, improve outcomes, and decrease costs for all patients.