Biomarkers to decide red blood cell transfusion in newborn infants | Zendy

Banerjee Jayanta | Zendy; Aladangady Narendra | Zendy

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Biomarkers to decide red blood cell transfusion in newborn infants

Author(s) -

Banerjee Jayanta,

Aladangady Narendra

Publication year - 2014

Publication title -

transfusion

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.045

H-Index - 132

eISSN - 1537-2995

pISSN - 0041-1132

DOI - 10.1111/trf.12670

Subject(s) - medicine , hematocrit , red blood cell transfusion , red blood cell , hemoglobin , intensive care medicine , blood transfusion , cardiorespiratory fitness , pediatrics , physiology

Almost 90% of extremely low birthweight infants receive red blood cell ( RBC ) transfusion during their stay in the neonatal unit ( NNU ). Currently most NNU s use a combination of clinical signs and laboratory findings such as hemoglobin ( Hb ), hematocrit ( Hct ), and cardiorespiratory or ventilation status to decide the need for RBC transfusion. Various other laboratory (lactate, reticulocyte count, RBC volume) and bedside measurements (near infrared spectroscopy and D oppler ultrasound scan) have been investigated to identify a suitable trigger for RBC transfusion in newborn infants. The evidence to apply any of these investigations or measurements to clinical practice is lacking. Further research is required to identify a suitable biomarker for RBC transfusion in newborn infants.

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