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The outer membrane vesicles: Secretion system type zero
Author(s) -
GuerreroMandujano Andrea,
HernándezCortez Cecilia,
Ibarra Jose Antonio,
CastroEscarpulli Graciela
Publication year - 2017
Publication title -
traffic
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.677
H-Index - 130
eISSN - 1600-0854
pISSN - 1398-9219
DOI - 10.1111/tra.12488
Subject(s) - bacterial outer membrane , secretion , biology , vesicle , biomolecule , extracellular vesicles , extracellular , microbiology and biotechnology , inner membrane , nucleic acid , biophysics , membrane , biochemistry , escherichia coli , gene
Gram‐negative bacteria have mechanisms through which they can colonize and survive in different environments, such as the secretion systems types (1‐6) that have been widely studied and characterized. Nowadays, some authors have proposed extracellular structures, such as the outer membrane vesicles ( OMVs ), to be considered as an additional and independent secretion system. The OMVs are spherical particles of 50‐250 nm in diameter; they originate in the outer membrane, and therefore they have a very similar composition to the latter. These particles can transport an important variety of biomolecules: enzymes, toxins, antigenic determinants and even nucleic acids. Thus, it is of great interest to collect data describing the advantages of the transport of biomolecules through the OMVs and, thus, determine their role as a potential secretion system.