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Issue Cover (January 2015)
Publication year - 2015
Publication title -
traffic
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.677
H-Index - 130
eISSN - 1600-0854
pISSN - 1398-9219
DOI - 10.1111/tra.12252
Subject(s) - microtubule , microbiology and biotechnology , biology , spindle apparatus , spindle pole body , staining , cell , cell division , genetics
Cover legend: Structured Illumination Microscopy analysis of central spindle formation in control HeLa cells (left) and EHD1‐depleted Hela cells (right) . Microtubules were labeled with anti‐tubulin antibody (red) and the centralspindlin complex was labeled with anti‐MKLP1 antibody (green). In control cells, anti‐parallel microtubules bundle and punctate MKLP1 is found at the plus ends of central spindle microtubules. In EHD1‐depleted cells, central spindle microtubules are unorganized, display inefficient bundling and MKLP1 staining is elongated suggesting that EHD1 is required for proper central spindle formation. See Reinecke et al. Traffic 2015; 16(1):48–67. Read the full article on doi: 10.1111/tra.12234