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Issue Cover (November 2014)
Publication year - 2014
Publication title -
traffic
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.677
H-Index - 130
eISSN - 1600-0854
pISSN - 1398-9219
DOI - 10.1111/tra.12207
Subject(s) - capsid , viral tegument , biology , cover (algebra) , herpes simplex virus , microbiology and biotechnology , crystallography , biophysics , virology , virus , chemistry , mechanical engineering , engineering
Cover legend: Electron cryo tomography reveals specific surface features on Herpes Simplex Virus capsids capable of binding to nuclear pores (see Anderson, Savulescu et al., page 1271). Sub‐volume average of capsids isolated from intact virions by extraction with TX‐100 and 0.1 M KCl. The upper left panel shows a digital cross section and the upper right panel an iso‐surface representation. The surface of such capsid carry tegument densities (in red in the bottom panels) that confer binding to nuclear pores. These densities are attached to the pentons located at the capsid vertices (lower right panel). Images by Iosune Ibiricu and Kay Grünewald. See Anderson et al. Traffic 2014; 15(11):1266–1281. Read the full article on doi: 10.1111/tra.12209