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MOS 1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis
Author(s) -
Zhang Ning,
Wang Zhixue,
Bao Zhilong,
Yang Leiyun,
Wu Dianxing,
Shu Xiaoli,
Hua Jian
Publication year - 2018
Publication title -
the plant journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.058
H-Index - 269
eISSN - 1365-313X
pISSN - 0960-7412
DOI - 10.1111/tpj.13757
Subject(s) - arabidopsis , microbiology and biotechnology , cell cycle , chemistry , biology , cell , gene , biochemistry , mutant
Summary Emerging evidence indicates a close connection between cell‐cycle progression and the plant immune responses. In Arabidopsis, MODIFIER OF snc1‐1 ( MOS 1 ) modulates a number of processes including endoreduplication and plant disease resistance, but the molecular mechanism underlying this modulation was not fully understood. Here, we provide biochemical and genetic evidence that TEOSINTE BRANCHED 1, CYCLOIDEA , PCF 1 ( TCP ) transcription factors TCP 15 and its homologues are mediators of MOS 1 function in the immune response and are likely to be also involved in cell‐cycle control. MOS 1 and TCP proteins have a direct physical interaction. They both bind to the promoter of the immune receptor gene SUPRESSOR OF npr1‐1 , CONSTITUTIVE 1 ( SNC 1 ) and modulate its expression and consequently immune responses. MOS 1 and TCP 15 both affect the expression of cell‐cycle genes D‐type CYCLIN 3 ; 1 ( CYCD 3 ; 1 ), which may mediate the MOS 1 function in cell‐cycle modulation. In addition, CYCD 3 ; 1 overexpression upregulates immune responses, and SNC1 expression. This study investigated and revealed a role for MOS 1 in transcriptional regulation through TCP 15 and its homologues. This finding suggests the coordination of cell‐cycle progression and plant immune responses at multiple levels.