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In vitro maturation
Author(s) -
Vitek Wendy,
Robins Jared C
Publication year - 2013
Publication title -
the obstetrician and gynaecologist
Language(s) - English
Resource type - Journals
eISSN - 1744-4667
pISSN - 1467-2561
DOI - 10.1111/tog.12050
Subject(s) - in vitro maturation , in vitro fertilisation , polycystic ovary , in vitro , biology , andrology , pregnancy , medicine , oocyte , embryo , endocrinology , microbiology and biotechnology , genetics , diabetes mellitus , insulin resistance
Key content In vitro maturation is an alternative to in vitro fertilisation for young women with polycystic ovary syndrome and young ovulatory women. In vitro maturation accomplishes the maturation of immature oocytes in the laboratory, thus minimising or avoiding gonadotrophin stimulation and the associated cost, side‐effects and risks. Pregnancy rates are lower with in vitro maturation than with in vitro fertilisation.Learning objectives To define appropriate candidates for in vitro maturation. To review variations in protocols and laboratory aspects of in vitro maturation and the rationale for these variations. To highlight outcome data from in vitro maturation cycles.Ethical issues Infertile couples must consider both the risks and benefits of in vitro maturation and make an informed decision regarding their treatment options. Further long‐term outcome data regarding the health of children born through in vitro maturation is necessary.