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Tropical pyomyositis: an update
Author(s) -
Shittu Adebayo,
DeinhardtEmmer Stefanie,
Vas Nunes Jonathan,
Niemann Silke,
Grobusch Martin P.,
Schaumburg Frieder
Publication year - 2020
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/tmi.13395
Subject(s) - pyomyositis , microbiology and biotechnology , staphylococcus aureus , medicine , pseudomonas aeruginosa , immunology , biology , bacteria , abscess , surgery , genetics
Tropical pyomyositis (TP) is a life‐threatening bacterial infection of the skeletal muscle that occurs particularly among children, young adults and those with immunocompromised conditions. The appropriate diagnosis and treatment are often delayed due to its non‐specific signs, leading to fatal consequences. Staphylococcus aureus , especially methicillin‐susceptible S. aureus, is responsible for most TP cases. However, other bacteria (i.e. streptococci, Pseudomonas aeruginosa , Escherichia coli , Klebsiella spp . , Candida spp., Mycobacterium spp.) have been reported. This narrative review provides an update on the epidemiology and clinical course of TP. A special focus is laid on the role of toxins (i.e. Panton‐Valentine Leucocidin and α‐toxin) in the pathogenesis of TP and their implication for the clinical management of infection.