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Rapid diagnostic test for G6 PD deficiency in Plasmodium vivax ‐infected men: a budget impact analysis based in Brazilian Amazon
Author(s) -
Peixoto Henry Maia,
Brito Marcelo Augusto Mota,
Romero Gustavo Adolfo Sierra,
Monteiro Wuelton Marcelo,
Lacerda Marcus Vinícius Guimarães,
Oliveira Maria Regina Fernandes
Publication year - 2017
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/tmi.12800
Subject(s) - amazon rainforest , plasmodium vivax , rapid diagnostic test , malaria , medicine , diagnostic test , public health , environmental health , immunology , pediatrics , plasmodium falciparum , biology , pathology , ecology
Objective The aim of this study was to estimate the incremental budget impact ( IBI ) of a rapid diagnostic test to detect G6 PD d in male patients infected with Plasmodium vivax in the Brazilian Amazon, as compared with the routine protocol recommended in Brazil which does not include G6 PD d testing. Methods The budget impact analysis was performed from the perspective of the Brazilian health system, in the Brazilian Amazon for the years 2013, 2014 and 2015. The analysis used a decision model to compare two scenarios: the first consisting of the routine recommended in Brazil which does not include prior diagnosis of dG 6 PD , and the second based on the use of RDT CareStart™ G6 PD ( CS ‐G6 PD ) in all male subjects diagnosed with vivax malaria. The expected implementation of the diagnostic test was 30% in the first year, 70% the second year and 100% in the third year. Results The analysis identified negative IBI s which were progressively smaller in the 3 years evaluated. The sensitivity analysis showed that the uncertainties associated with the analytical model did not significantly affect the results. Conclusion A strategy based on the use of CS ‐G6 PD would result in better use of public resources in the Brazilian Amazon.