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Time to initiation of multidrug‐resistant tuberculosis treatment and its relation with outcome in a high incidence district in L ima, P eru
Author(s) -
Otero L.,
De Orbegoso A.,
Navarro A. F.,
Ríos J.,
Párraga T.,
Gotuzzo E.,
Seas C.,
Van der Stuyft P.
Publication year - 2015
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/tmi.12430
Subject(s) - incidence (geometry) , medicine , tuberculosis , multiple drug resistance , microbiology and biotechnology , biology , drug resistance , pathology , physics , optics
Abstract Objective To determine the time from diagnosis to start of multidrug resistant tuberculosis (MDR TB) treatment in L ima, P eru. Methods We studied new smear‐positive TB adults that were started on MDR TB treatment or that were switched to it between June 2008 and December 2011. Results Time from the first positive smear to MDR ‐ TB treatment was >30 days in 35% (13/37) of patients. Among the 27% (24/88) of patients that switched to MDR ‐ TB treatment, time from the last dose of a drug‐susceptible regimen was >30 days. Conclusion Start of and switching to MDR TB treatment is still delayed.