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Oral susceptibility of Aedes aegypti (Diptera: Culicidae) from Senegal for dengue serotypes 1 and 3 viruses
Author(s) -
Gaye Alioune,
Faye Oumar,
Diagne Cheikh T.,
Faye Ousmane,
Diallo Diawo,
Weaver Scott C.,
Sall Amadou A.,
Diallo Mawlouth
Publication year - 2014
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/tmi.12373
Subject(s) - aedes aegypti , dengue fever , serotype , virology , dengue virus , biology , population , aedes , incubation period , veterinary medicine , medicine , incubation , environmental health , ecology , larva , biochemistry
Objective To investigate the potential for domestic and wild populations of Aedes aegypti from Dakar and Kedougou to develop a disseminated infection after exposure to DENV ‐3 and DENV ‐1. Methods We have exposed sylvatic and urban population of Ae. aegypti from Senegal to bloomeals containing dengue serotype 1 and 3. At different incubation period, individual mosquito legs/wings and bodies were tested for virus presence using real time RT–PCR to estimate the infection and dissemination rates. Results The data indicated low susceptibility to DENV ‐3 (infection: 2.4–15.2%, and dissemination rates: 0–8.3%) and higher susceptibility to DENV ‐1 (infection and dissemination rates up to 50%). Conclusion Aedes aegypti from Senegal seem able to develop a disseminated infection of DENV ‐1 and DENV ‐3. Further studies are needed to test their ability to transmit the two serotypes.