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Elucidating the temporal and spatial dynamics of B iomphalaria glabrata genetic diversity in three B razilian villages
Author(s) -
Thiele Elizabeth A.,
CorrêaOliveira Guilherme,
Gazzinelli Andrea,
Minchella Dennis J.
Publication year - 2013
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1111/tmi.12164
Subject(s) - biology , genetic diversity , snail , gene flow , population , biomphalaria , biomphalaria glabrata , genetic variation , ecology , intermediate host , genetic variability , population genetics , locus (genetics) , schistosoma mansoni , zoology , evolutionary biology , host (biology) , helminths , genetics , gene , schistosomiasis , genotype , demography , sociology
Objective The freshwater snail B iomphalaria glabrata is the principal intermediate host for the parasite S chistosoma mansoni within B razil. We assessed the potential effects of snail population dynamics on parasite transmission dynamics via population genetics. Methods We sampled snail populations located within the confines of three schistosome‐endemic villages in the state of M inas G erais, B razil. Snails were collected from individual microhabitats following seasonal periods of flood and drought over the span of 1 year. Snail spatio‐temporal genetic diversity and population differentiation of 598 snails from 12 sites were assessed at seven microsatellite loci. Results Average genetic diversity was relatively low, ranging from 4.29 to 9.43 alleles per locus, and overall, subpopulations tended to exhibit heterozygote deficits. Genetic diversity was highly spatially partitioned among subpopulations, while virtually, no partitioning was observed across temporal sampling. Comparison with previously published parasite genetic diversity data indicated that S. mansoni populations are significantly more variable and less subdivided than those of the B. glabrata intermediate hosts. Discussion Within individual B razilian villages, observed distributions of snail genetic diversity indicate temporal stability and very restricted gene flow. This is contrary to observations of schistosome genetic diversity over the same spatial scale, corroborating the expectation that parasite gene flow at the level of individual villages is likely driven by vertebrate host movement.