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Diagnosis of central nervous system invasive aspergillosis in a liver transplant recipient using microbial cell‐free next generation DNA sequencing
Author(s) -
Shishido Akira A.,
Vostal Alexander,
Mayer Romana,
Ho ChengYing,
Baddley John W
Publication year - 2021
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.13592
Subject(s) - aspergillosis , medicine , central nervous system , dna sequencing , liver abscess , liver transplantation , pathology , immunology , dna , abscess , transplantation , biology , surgery , genetics
Invasive aspergillosis (IA) is an important opportunistic infection among patients with liver disease and liver transplants. Diagnosis of IA may be challenging, especially among patients with central nervous system infection. Herein, we demonstrate the utility of next‐generation sequencing of microbial cell‐free DNA in the diagnosis of fungal brain abscess in a liver transplant recipient.