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Donor‐derived renal allograft mucormycosis in a combined liver and kidney transplantation: Case report and review of the literature
Author(s) -
Thatipelli Sneha,
Santoiemma Phillip,
Echenique Ignacio A.,
Green Richard,
Ison Michael G.,
Ladner Daniela,
Kanwar Yashpal S.,
Stosor Valentina
Publication year - 2021
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.13534
Subject(s) - medicine , mucormycosis , transplantation , kidney , kidney transplantation , surgery , posaconazole , urinary system , amphotericin b , antifungal , dermatology
Mucormycosis infrequently may present with isolated renal involvement. Among solid organ transplant recipients, renal allograft mucormycosis has been most often associated with medical tourism or transplantation outside of the western world. We report a case of an HIV/HCV co‐infected woman who underwent simultaneous liver and kidney transplantation with a Public Health Service increased risk donor organ. 16 days after transplant, she developed massive hematuria and was found to have renal allograft Rhizopus spp. involvement, we surmise to have been from donor‐derived infection. Therapy included nephrectomy, debridement, liposomal amphotericin B, and posaconazole with survival. We reviewed PubMed indexed, English‐language cases of isolated renal mucormycosis in general, in HIV/AIDS, and from donor‐derived renal allograft infections.