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Cerebral abscess and calvarial osteomyelitis caused by Burkholderia pseudomallei in a renal transplant recipient
Author(s) -
Muthina Raja Amarendra,
Koppara Naveen Kumar,
Bethasaida Manuel Maria,
Bommu Alekhya Naga,
Anapalli Sunnesh Reddy,
Boju Sangeetha Lakshmi,
Rapur Ram,
Vishnubotla Siva Kumar
Publication year - 2021
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.13530
Subject(s) - burkholderia pseudomallei , melioidosis , medicine , osteomyelitis , ceftazidime , abscess , brain abscess , sulfamethoxazole , burkholderia , trimethoprim , renal transplant , surgery , microbiology and biotechnology , pathology , antibiotics , transplantation , pseudomonas aeruginosa , bacteria , biology , genetics
Melioidosis is an infection of humans caused by the saprophytic bacterium Burkholderia (previously Pseudomonas) pseudomallei . We present a patient of cerebral abscess and calvarial osteomyelitis caused by B. pseudomallei in a renal transplant recipient. We treated the patient with ceftazidime for 3 weeks, followed by trimethoprim‐sulfamethoxazole (TMP‐SMX) for 6 months. The superficial abscess reduced in size at the end of first month and subsided gradually. A repeat MRI showed reduction in intracranial abscess. The patient had no neurological deficit.