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Kinetics of torquetenovirus DNA load in a recent kidney transplant recipient with mild SARS‐CoV‐2 infection and a failed antibody response
Author(s) -
Querido Sara,
Calça Rita,
Weigert André,
Francisco Diogo,
Adragão Teresa,
Ana Pessanha Maria,
Gomes Perpétua,
Rodrigues Luís,
Figueira João M.,
Cardoso Conceição,
Machado Domingos
Publication year - 2021
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.13524
Subject(s) - medicine , antibody response , covid-19 , kidney transplant , immunology , antibody , virology , viral load , kidney transplantation , kidney , virus , outbreak , infectious disease (medical specialty) , disease
Kidney transplant (KT) recipients are at an increased risk for severe COVID‐19 because of their immunosuppressed state. A 42‐year‐old KT patient was diagnosed with COVID‐19 three months after KT. Despite lymphopenia and several risk factors, he had a mild disease course. Nasopharyngeal real‐time reverse transcriptase polymerase chain reaction for SARS‐CoV‐2 became negative 48 days after detection. SARS‑CoV‑2 IgG antibodies became negative after day 40. TTV DNA load increased with the onset COVID‐19 and reduced after its resolution. This is the first report where TTV DNA load was measured during the course of COVID‐19.