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Successful liver transplantation in a patient recovered from COVID‐19
Author(s) -
Dhand Abhay,
Bodin Roxana,
Wolf David C.,
Schluger Aaron,
Nabors Christopher,
Nog Rajat,
Diflo Thomas,
Nishida Seigo
Publication year - 2021
Publication title -
transplant infectious disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.69
H-Index - 67
eISSN - 1399-3062
pISSN - 1398-2273
DOI - 10.1111/tid.13492
Subject(s) - medicine , immunosuppression , covid-19 , liver transplantation , transplantation , organ transplantation , viral shedding , immune system , intensive care medicine , immunology , virus , pathology , disease , outbreak , infectious disease (medical specialty)
Abstract Transplantation in potential candidates who have recently recovered from COVID‐19 is a challenge with uncertainties regarding the diagnosis, multi‐organ systemic involvement, prolonged viral shedding in immunocompromised patients, and optimal immunosuppression. A 42 year male with alcoholic hepatitis underwent a successful deceased donor liver transplantation 71 days after the initial diagnosis of COVID‐19. At the time of transplant, he was SARS‐CoV‐2 PCR negative for 24 days and had a MELD score of 33. His post‐operative course was complicated by acute rejection which responded to intense immune‐suppression using T‐cell depletion and steroids. He was discharged with normal end‐organ function and no evidence of any active infection including COVID‐19. Prospective organ transplant recipients who have recovered from COVID‐19 can be considered for transplantation after careful pre‐transplant evaluation, donor selection, and individualized risk‐benefit analysis.